UX Report:
Revenue & NPS Drivers in DTC Genetic Testing

30 min
UX Impact Report: Revenue & NPS Drivers in DTC Genetic Testing Cieden

TL;DR

  • 3 bullet points in core friction points with data
  • 3 points on winning features

Note on methodology

I reviewed user feedback and discussions on nine Direct-to-Consumer (DTC) genetic testing tools: 23andMe, AncestryDNA, MyHeritage DNA, FamilyTreeDNA (FTDNA), Living DNA, Dante Labs, Nebula Genomics, GEDmatch, and 3X4 Genetics. The platforms I went through were Trustpilot, G2, Capterra, Reddit, Quora, and 300 other product review sites. 

The goal was to identify the most and least praised UX themes by users that led them to recommend a product or caution against its usage.

3 UX friction points and solutions

Billing confusion, poor data clarity, and navigation issues are key recurring patterns that turn users away. Below, I briefly deconstruct them and provide advice of what could be a good starting point for a solution strategy.

Pattern 1: Users feel they were mischarged

This pattern is present in all nine products. Users caution others not to try a product because of paywall "betrayal", holding the data "hostage," difficult cancellation, and billing for a full year upfront for a service advertised with a monthly fee.

Trust-eroding billing practices
Trust-eroding billing practices
Product Misleading charges Paywalling core features Holding data "hostage" Difficult cancellation Total complaints
23andMe 4 5 4 1 14
AncestryDNA 4 7 1 4 16
MyHeritage DNA 4 5 0 1 10
Dante Labs 4 0 5 3 12
Nebula Genomics 1 0 2 1 4
FamilyTreeDNA (FTDNA) 1 0 0 0 1
Living DNA 0 0 0 0 0
GEDmatch 0 1 0 0 1
3X4 Genetics 0 0 1 0 1

Here is a breakdown of the reasons that lie under the issue of ‘mischarges.’

Strategic Challenges Cards
Challenge 01

Monetization

Strategic conflict between short-term financial targets and long-term user trust

Click to explore challenge

Monetization

A strategic conflict between short-term financial targets and long-term user trust. Because one-time kit sales are unprofitable due to high customer acquisition costs and market saturation, the business is forced to prioritize Annual Recurring Revenue (ARR) to satisfy investors.

This creates an urgent, short-term priority: maximize subscription revenue at all costs. Consequently, a poor user experience – like a confusing cancellation process or a misleading paywall – is not an accident.

Challenge 02

Wrong KPIs and silos

Conflicting departmental goals leading to fragmented user experience

Click to explore challenge

Wrong KPIs and silos

Conflicting departmental goals (product, marketing, customer service) lead to a poor user experience. Product teams prioritize KPIs like subscription rates, potentially at odds with user-friendly features like clear billing.

This lack of a unified customer-centric vision harms the overall user experience. Each department optimizes for their own metrics without considering the holistic customer journey.

Challenge 03

The "value perception" gap

Misalignment between company justification and customer expectations

Click to explore challenge

The "value perception" gap

The company justifies subscriptions by offering continuous value through research, DNA matches, and updates, while customers perceive the product as a one-time purchase.

This fundamental misalignment creates friction when customers encounter subscription requirements for features they expected to be included with their initial purchase.

Challenge 04

Legacy systems

Inflexible billing infrastructure creating user experience limitations

Click to explore challenge

Legacy systems

Billing and subscription systems, initially designed for one-time purchases, are inflexible and buggy. These legacy architectures struggle to handle the complexity of modern subscription models.

A complete architectural overhaul is needed, but it's too costly. Companies are trapped between maintaining poor user experiences and investing significant resources in system modernization.

Challenge 05

Complexity of global billing

Backend systems stretched beyond limits affecting user experience

Click to explore challenge

Complexity of global billing

Managing subscriptions, taxes (VAT), currencies, and different regional promotions is immensely complex. The technical infrastructure required to handle global billing creates multiple points of failure.

Sometimes, a poor user experience is an unfortunate byproduct of a backend system stretched to its limits. The complexity of global compliance often forces compromises in user-facing functionality.

Why it needs to be changed

Short-term subscription boosts from deceptive tactics mortgage the product's future, as these "ghost" users will churn and not return. True LTV comes from engaged users who willingly stay and are open to upsells.

The product team overspends on acquiring new users to replace angry ones, creating a treadmill, not growth. Fixing UX and building trust reduces "bad" churn, stabilizing ARR.

Without change, marketing and support costs will plummet. Negative reviews, amplified by crawlers, necessitate significant advertising spend to combat search results filled with "scam" warnings.

What the right UX can solve

Flip Solution Strategy Cards
Solution 01

Balance the value exchange

Transform user "betrayal" into ongoing value perception

Click to explore solution

Balance the value exchange

The user feeling of "betrayal" when features are moved behind a paywall.

You can facilitate workshops with key stakeholders (product, marketing, leadership) to shift the narrative from "we need subscribers" to "we must deliver continuous value." The output is a Value Proposition Canvas for the subscription itself. It answers the user's question: "Why should I pay you on an ongoing basis?"

A clear, documented strategy for communicating ongoing value. For example, instead of just locking a feature, the UI explicitly states: "Your subscription funds ongoing research, which allowed us to launch this new trait report. See your results now."

Solution 02

Eliminate silos

Bridge marketing promises with product reality

Click to explore solution

Eliminate silos

The "Cancellation maze" and the "free trial" trap, which are born from a disconnect between marketing promises and product reality.

Conduct a comprehensive audit of the entire customer journey, from the first ad they see to the moment they try to cancel. This visual map highlights points of friction, confusion, and "trust-breaking" moments.

A detailed customer journey map that shows exactly where the experience breaks down. This tool shows executives from different departments (the "siloes") how their collective actions create a negative experience. It would visually pinpoint, "The marketing email promises X, but the checkout flow charges Y, and the support FAQ says Z."

Solution 03

Improve retention

Convert executive priorities with data-driven insights

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Improve retention

The executive mindset that prioritizes short-term subscription numbers over user sentiment.

The analysts would correlate the existing "bad UX" with negative business metrics that executives care about:

  • Calculate the cost of support tickets related to billing complaints.
  • Analyze app store reviews and NPS data to quantify brand damage.
  • Model the potential increase in LTV from users who choose to stay subscribed versus those who simply forget to cancel (the latter have a very high churn rate the moment they notice the charge).

An ROI report that argues: "By investing $X in redesigning our cancellation flow, we can reduce support costs by Y% and improve long-term retention by Z%, leading to a more stable revenue base."

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Pattern 2: Users struggle to understand the data

The genetics industry faces a systemic challenge to deliver the core value proposition of a DNA test: translating raw, complex genetic data into meaningful, understandable, and actionable insights for a non-expert audience. The most common failures are not technical bugs but flaws in design, communication, and user education that create significant friction for customers.

This pattern is present in all studied products.

Insight delivery failures
Insight delivery failures
Company Total identified reviews Unexplained jargon Ambiguous & vague results Static/non-interactive reports Other UI/UX issues
23andMe 11 0 8 0 3
AncestryDNA 7 1 4 0 2
MyHeritage DNA 2 0 1 1 0
FamilyTreeDNA 5 0 4 0 1
Living DNA 5 0 5 0 0
Dante Labs 6 1 3 2 0
Nebula Genomics 4 1 2 0 1
GEDmatch 3 1 0 0 2
3X4 Genetics 3 1 0 2 0

Here's a breakdown of the reasons contributing to the 'data-insight delivery' problem.

Consumer Genomics Challenge Cards
Challenge 06

Weaponized jargon

Technical language alienating users instead of educating them

Click to explore challenge

Weaponized jargon

Many consumer genomics companies, founded by scientists and bioinformaticians, developed science-led cultures that prioritize algorithms and raw data over user experience. This contrasts with product-led organizations that integrate user-centered design as a core competency.

With platforms like GEDmatch and Dante Labs, technical language is used in a way that alienates rather than educates. The interfaces are saturated with essential, discipline-specific terminology – such as cM, SNP, Autosomal, and Haplogroup – without any in-context definitions, tooltips, or integrated glossaries.

This failure forces users into a frustrating cycle of leaving the platform to conduct external research simply to understand its basic functions.

Challenge 07

Crisis of ambiguity

Vague results and demographic bias undermining user trust

Click to explore challenge

Crisis of ambiguity

DTC genetic testing platforms often disappoint users due to vague or changing ethnicity estimates. This stems from marketing promoting definitive answers, while the science is probabilistic and evolving. Users perceive broad results as product failures rather than scientific limitations.

The root cause is a demographic imbalance in genomic reference databases. For example, 23andMe's European dataset is significantly larger than its Asian and Sub-Saharan African sets (800% and 2800% respectively). This Eurocentric bias makes the product less accurate for a large portion of its global customer base.

The disparity leads to more "variants of uncertain significance" (VUS) for non-white patients, causing distress and confusion while eroding trust in the platform.

Challenge 08

Non-interactive reports

Static formats limiting user exploration and data ownership

Click to explore challenge

Non-interactive reports

DTC genetic testing tools often fail by delivering complex genetic analysis in static formats like PDFs, hindering user interaction and exploration. Companies like 3X4 don't allow users to download their raw data, while AncestryDNA and MyHeritage create "stopping point" experiences.

Users want to interact with genomic data – explore, filter, compare, question, and seek outside perspectives – not just view it. They expect data ownership and portability as fundamental rights.

Non-interactive platforms or those lacking manipulation tools limit exploration and fall short of user expectations, creating frustration and reducing the perceived value of genetic testing services.

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